diff --git a/Cargo.lock b/Cargo.lock
index afa753871..afd186fa6 100644
--- a/Cargo.lock
+++ b/Cargo.lock
@@ -1042,20 +1042,20 @@ dependencies = [
 
 [[package]]
 name = "kvm-bindings"
-version = "0.10.0"
+version = "0.12.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "fa4933174d0cc4b77b958578cd45784071cc5ae212c2d78fbd755aaaa6dfa71a"
+checksum = "d4b153a59bb3ca930ff8148655b2ef68c34259a623ae08cf2fb9b570b2e45363"
 dependencies = [
  "serde",
  "vmm-sys-util",
- "zerocopy 0.7.35",
+ "zerocopy 0.8.26",
 ]
 
 [[package]]
 name = "kvm-ioctls"
-version = "0.19.1"
+version = "0.22.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "e013ae7fcd2c6a8f384104d16afe7ea02969301ea2bb2a56e44b011ebc907cab"
+checksum = "b702df98508cb63ad89dd9beb9f6409761b30edca10d48e57941d3f11513a006"
 dependencies = [
  "bitflags 2.9.0",
  "kvm-bindings",
@@ -1183,7 +1183,7 @@ dependencies = [
 [[package]]
 name = "micro_http"
 version = "0.1.0"
-source = "git+https://github.com/firecracker-microvm/micro-http?branch=main#4f621532e81ee2ad096a9c9592fdacc40d19de48"
+source = "git+https://github.com/firecracker-microvm/micro-http?branch=main#bf5098916006912f8dd35aaa6daa5579c6c297b2"
 dependencies = [
  "libc",
  "vmm-sys-util",
@@ -2188,21 +2188,9 @@ dependencies = [
  "getrandom 0.3.3",
  "js-sys",
  "rand",
- "uuid-macro-internal",
  "wasm-bindgen",
 ]
 
-[[package]]
-name = "uuid-macro-internal"
-version = "1.17.0"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "26b682e8c381995ea03130e381928e0e005b7c9eb483c6c8682f50e07b33c2b7"
-dependencies = [
- "proc-macro2",
- "quote",
- "syn",
-]
-
 [[package]]
 name = "vcpkg"
 version = "0.2.15"
@@ -2211,16 +2199,18 @@ checksum = "accd4ea62f7bb7a82fe23066fb0957d48ef677f6eeb8215f372f52e48bb32426"
 
 [[package]]
 name = "vfio-bindings"
-version = "0.4.0"
-source = "git+https://github.com/rust-vmm/vfio?branch=main#3d158a14460cac7ca3c99c2effa0a46880935cb0"
+version = "0.5.0"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "b565663f62e091ca47db9a674c8c95c9686a000e82970f391a3cacf6470ff060"
 dependencies = [
  "vmm-sys-util",
 ]
 
 [[package]]
 name = "vfio-ioctls"
-version = "0.4.0"
-source = "git+https://github.com/rust-vmm/vfio?branch=main#3d158a14460cac7ca3c99c2effa0a46880935cb0"
+version = "0.5.0"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "61316b5e308faa8ed4a87c4130256f765e46de3442eb2e2e619840ef73456738"
 dependencies = [
  "byteorder",
  "kvm-bindings",
@@ -2229,7 +2219,7 @@ dependencies = [
  "log",
  "mshv-bindings",
  "mshv-ioctls",
- "thiserror 1.0.62",
+ "thiserror 2.0.12",
  "vfio-bindings",
  "vm-memory",
  "vmm-sys-util",
@@ -2238,15 +2228,16 @@ dependencies = [
 [[package]]
 name = "vfio_user"
 version = "0.1.0"
-source = "git+https://github.com/rust-vmm/vfio-user?branch=main#3febcdd3fa2531623865663ca1721e1962ed9979"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "ed81c5ed8224d468a322e923777ed0615cad433fe61177126098af995f89cecf"
 dependencies = [
- "bitflags 1.3.2",
+ "bitflags 2.9.0",
  "libc",
  "log",
  "serde",
  "serde_derive",
  "serde_json",
- "thiserror 1.0.62",
+ "thiserror 2.0.12",
  "vfio-bindings",
  "vm-memory",
  "vmm-sys-util",
@@ -2254,8 +2245,9 @@ dependencies = [
 
 [[package]]
 name = "vhost"
-version = "0.12.1"
-source = "git+https://github.com/rust-vmm/vhost?rev=d983ae0#d983ae07f78663b7d24059667376992460b571a2"
+version = "0.14.0"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "2a4dcad85a129d97d5d4b2f3c47a4affdeedd76bdcd02094bcb5d9b76cac2d05"
 dependencies = [
  "bitflags 2.9.0",
  "libc",
@@ -2266,8 +2258,9 @@ dependencies = [
 
 [[package]]
 name = "vhost-user-backend"
-version = "0.16.1"
-source = "git+https://github.com/rust-vmm/vhost?rev=d983ae0#d983ae07f78663b7d24059667376992460b571a2"
+version = "0.20.0"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "e183205a9ba7cb9c47fcb0fc0a07fc295a110efbb11ab78ad0d793b0a38a7bde"
 dependencies = [
  "libc",
  "log",
@@ -2319,9 +2312,9 @@ dependencies = [
 
 [[package]]
 name = "virtio-bindings"
-version = "0.2.4"
+version = "0.2.6"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "1711e61c00f8cb450bd15368152a1e37a12ef195008ddc7d0f4812f9e2b30a68"
+checksum = "804f498a26d5a63be7bbb8bdcd3869c3f286c4c4a17108905276454da0caf8cb"
 
 [[package]]
 name = "virtio-devices"
@@ -2359,9 +2352,9 @@ dependencies = [
 
 [[package]]
 name = "virtio-queue"
-version = "0.14.0"
+version = "0.16.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "872e2f3fbd70a7e6f01689720cce3d5c2c5efe52b484dd07b674246ada0e9a8d"
+checksum = "fb0479158f863e59323771a1f684d843962f76960b86fecfec2bfa9c8f0f9180"
 dependencies = [
  "log",
  "virtio-bindings",
@@ -2398,9 +2391,9 @@ source = "git+https://github.com/rust-vmm/vm-fdt?branch=main#ef5bd734f5f66fb0772
 
 [[package]]
 name = "vm-memory"
-version = "0.16.1"
+version = "0.16.2"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "f1720e7240cdc739f935456eb77f370d7e9b2a3909204da1e2b47bef1137a013"
+checksum = "1fd5e56d48353c5f54ef50bd158a0452fc82f5383da840f7b8efc31695dd3b9d"
 dependencies = [
  "arc-swap",
  "libc",
@@ -2489,9 +2482,9 @@ dependencies = [
 
 [[package]]
 name = "vmm-sys-util"
-version = "0.12.1"
+version = "0.14.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "1d1435039746e20da4f8d507a72ee1b916f7b4b05af7a91c093d2c6561934ede"
+checksum = "d21f366bf22bfba3e868349978766a965cbe628c323d58e026be80b8357ab789"
 dependencies = [
  "bitflags 1.3.2",
  "libc",
diff --git a/Cargo.toml b/Cargo.toml
index fefbd227e..0cc8e53a9 100644
--- a/Cargo.toml
+++ b/Cargo.toml
@@ -103,22 +103,22 @@ members = [
 [workspace.dependencies]
 # rust-vmm crates
 acpi_tables = { git = "https://github.com/rust-vmm/acpi_tables", branch = "main" }
-kvm-bindings = "0.10.0"
-kvm-ioctls = "0.19.1"
+kvm-bindings = "0.12.0"
+kvm-ioctls = "0.22.0"
 linux-loader = "0.13.0"
 mshv-bindings = "0.5.1"
 mshv-ioctls = "0.5.1"
 seccompiler = "0.5.0"
-vfio-bindings = { git = "https://github.com/rust-vmm/vfio", branch = "main" }
-vfio-ioctls = { git = "https://github.com/rust-vmm/vfio", branch = "main", default-features = false }
-vfio_user = { git = "https://github.com/rust-vmm/vfio-user", branch = "main" }
-vhost = { git = "https://github.com/rust-vmm/vhost", rev = "d983ae0" }
-vhost-user-backend = { git = "https://github.com/rust-vmm/vhost", rev = "d983ae0" }
-virtio-bindings = "0.2.4"
-virtio-queue = "0.14.0"
+vfio-bindings = { version = "0.5.0", default-features = false }
+vfio-ioctls = { version = "0.5.0", default-features = false }
+vfio_user = { version = "0.1.0", default-features = false }
+vhost = { version = "0.14.0", default-features = false }
+vhost-user-backend = { version = "0.20.0", default-features = false }
+virtio-bindings = "0.2.6"
+virtio-queue = "0.16.0"
 vm-fdt = { git = "https://github.com/rust-vmm/vm-fdt", branch = "main" }
 vm-memory = "0.16.1"
-vmm-sys-util = "0.12.1"
+vmm-sys-util = "0.14.0"
 
 # igvm crates
 # TODO: bump to 0.3.5 release
diff --git a/block/Cargo.toml b/block/Cargo.toml
index 02bf37eb0..48551251a 100644
--- a/block/Cargo.toml
+++ b/block/Cargo.toml
@@ -19,7 +19,7 @@ serde = { version = "1.0.208", features = ["derive"] }
 smallvec = "1.13.2"
 thiserror = { workspace = true }
 uuid = { workspace = true, features = ["v4"] }
-virtio-bindings = { workspace = true, features = ["virtio-v5_0_0"] }
+virtio-bindings = { workspace = true }
 virtio-queue = { workspace = true }
 vm-memory = { workspace = true, features = [
   "backend-atomic",
diff --git a/block/src/lib.rs b/block/src/lib.rs
index 1424848ba..b081c8773 100644
--- a/block/src/lib.rs
+++ b/block/src/lib.rs
@@ -57,7 +57,7 @@ use vm_memory::{
 };
 use vm_virtio::{AccessPlatform, Translatable};
 use vmm_sys_util::eventfd::EventFd;
-use vmm_sys_util::{aio, ioctl_io_nr, ioctl_ioc_nr};
+use vmm_sys_util::{aio, ioctl_io_nr};
 
 use crate::async_io::{AsyncIo, AsyncIoError, AsyncIoResult};
 use crate::vhdx::VhdxError;
diff --git a/fuzz/Cargo.lock b/fuzz/Cargo.lock
index 967c05744..85596958c 100644
--- a/fuzz/Cargo.lock
+++ b/fuzz/Cargo.lock
@@ -7,7 +7,7 @@ name = "acpi_tables"
 version = "0.1.0"
 source = "git+https://github.com/rust-vmm/acpi_tables?branch=main#e08a3f0b0a59b98859dbf59f5aa7fd4d2eb4018a"
 dependencies = [
- "zerocopy 0.8.24",
+ "zerocopy 0.8.26",
 ]
 
 [[package]]
@@ -480,7 +480,7 @@ dependencies = [
  "vfio-ioctls",
  "vm-memory",
  "vmm-sys-util",
- "zerocopy 0.8.24",
+ "zerocopy 0.8.26",
 ]
 
 [[package]]
@@ -531,29 +531,30 @@ dependencies = [
 
 [[package]]
 name = "js-sys"
-version = "0.3.69"
+version = "0.3.77"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "29c15563dc2726973df627357ce0c9ddddbea194836909d655df6a75d2cf296d"
+checksum = "1cfaf33c695fc6e08064efbc1f72ec937429614f25eef83af942d0e227c3a28f"
 dependencies = [
+ "once_cell",
  "wasm-bindgen",
 ]
 
 [[package]]
 name = "kvm-bindings"
-version = "0.10.0"
+version = "0.12.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "fa4933174d0cc4b77b958578cd45784071cc5ae212c2d78fbd755aaaa6dfa71a"
+checksum = "d4b153a59bb3ca930ff8148655b2ef68c34259a623ae08cf2fb9b570b2e45363"
 dependencies = [
  "serde",
  "vmm-sys-util",
- "zerocopy 0.7.35",
+ "zerocopy 0.8.26",
 ]
 
 [[package]]
 name = "kvm-ioctls"
-version = "0.19.1"
+version = "0.22.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "e013ae7fcd2c6a8f384104d16afe7ea02969301ea2bb2a56e44b011ebc907cab"
+checksum = "b702df98508cb63ad89dd9beb9f6409761b30edca10d48e57941d3f11513a006"
 dependencies = [
  "bitflags 2.9.0",
  "kvm-bindings",
@@ -635,7 +636,7 @@ checksum = "78ca9ab1a0babb1e7d5695e3530886289c18cf2f87ec19a575a0abdce112e3a3"
 [[package]]
 name = "micro_http"
 version = "0.1.0"
-source = "git+https://github.com/firecracker-microvm/micro-http?branch=main#4f621532e81ee2ad096a9c9592fdacc40d19de48"
+source = "git+https://github.com/firecracker-microvm/micro-http?branch=main#bf5098916006912f8dd35aaa6daa5579c6c297b2"
 dependencies = [
  "libc",
  "vmm-sys-util",
@@ -652,7 +653,7 @@ dependencies = [
  "serde",
  "serde_derive",
  "vmm-sys-util",
- "zerocopy 0.8.24",
+ "zerocopy 0.8.26",
 ]
 
 [[package]]
@@ -830,7 +831,7 @@ checksum = "3779b94aeb87e8bd4e834cee3650289ee9e0d5677f976ecdb6d219e5f4f6cd94"
 dependencies = [
  "rand_chacha",
  "rand_core",
- "zerocopy 0.8.24",
+ "zerocopy 0.8.26",
 ]
 
 [[package]]
@@ -865,15 +866,21 @@ dependencies = [
 
 [[package]]
 name = "remain"
-version = "0.2.14"
+version = "0.2.15"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "46aef80f842736de545ada6ec65b81ee91504efd6853f4b96de7414c42ae7443"
+checksum = "d7ef12e84481ab4006cb942f8682bba28ece7270743e649442027c5db87df126"
 dependencies = [
  "proc-macro2",
  "quote",
  "syn",
 ]
 
+[[package]]
+name = "rustversion"
+version = "1.0.21"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "8a0d197bd2c9dc6e53b84da9556a69ba4cdfab8619eb41a8bd1cc2027a0f6b1d"
+
 [[package]]
 name = "ryu"
 version = "1.0.18"
@@ -1105,45 +1112,37 @@ checksum = "06abde3611657adf66d383f00b093d7faecc7fa57071cce2578660c9f1010821"
 
 [[package]]
 name = "uuid"
-version = "1.15.1"
+version = "1.17.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "e0f540e3240398cce6128b64ba83fdbdd86129c16a3aa1a3a252efd66eb3d587"
+checksum = "3cf4199d1e5d15ddd86a694e4d0dffa9c323ce759fea589f00fef9d81cc1931d"
 dependencies = [
  "getrandom 0.3.3",
+ "js-sys",
  "rand",
- "uuid-macro-internal",
-]
-
-[[package]]
-name = "uuid-macro-internal"
-version = "1.15.1"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "9521621447c21497fac206ffe6e9f642f977c4f82eeba9201055f64884d9cb01"
-dependencies = [
- "proc-macro2",
- "quote",
- "syn",
+ "wasm-bindgen",
 ]
 
 [[package]]
 name = "vfio-bindings"
-version = "0.4.0"
-source = "git+https://github.com/rust-vmm/vfio?branch=main#b135b8305c2cc8ec333e0cf77a780445cc98dcee"
+version = "0.5.0"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "b565663f62e091ca47db9a674c8c95c9686a000e82970f391a3cacf6470ff060"
 dependencies = [
  "vmm-sys-util",
 ]
 
 [[package]]
 name = "vfio-ioctls"
-version = "0.2.0"
-source = "git+https://github.com/rust-vmm/vfio?branch=main#b135b8305c2cc8ec333e0cf77a780445cc98dcee"
+version = "0.5.0"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "61316b5e308faa8ed4a87c4130256f765e46de3442eb2e2e619840ef73456738"
 dependencies = [
  "byteorder",
  "kvm-bindings",
  "kvm-ioctls",
  "libc",
  "log",
- "thiserror 1.0.64",
+ "thiserror 2.0.12",
  "vfio-bindings",
  "vm-memory",
  "vmm-sys-util",
@@ -1152,15 +1151,16 @@ dependencies = [
 [[package]]
 name = "vfio_user"
 version = "0.1.0"
-source = "git+https://github.com/rust-vmm/vfio-user?branch=main#3febcdd3fa2531623865663ca1721e1962ed9979"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "ed81c5ed8224d468a322e923777ed0615cad433fe61177126098af995f89cecf"
 dependencies = [
- "bitflags 1.3.2",
+ "bitflags 2.9.0",
  "libc",
  "log",
  "serde",
  "serde_derive",
  "serde_json",
- "thiserror 1.0.64",
+ "thiserror 2.0.12",
  "vfio-bindings",
  "vm-memory",
  "vmm-sys-util",
@@ -1168,8 +1168,9 @@ dependencies = [
 
 [[package]]
 name = "vhost"
-version = "0.12.1"
-source = "git+https://github.com/rust-vmm/vhost?rev=d983ae0#d983ae07f78663b7d24059667376992460b571a2"
+version = "0.14.0"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "2a4dcad85a129d97d5d4b2f3c47a4affdeedd76bdcd02094bcb5d9b76cac2d05"
 dependencies = [
  "bitflags 2.9.0",
  "libc",
@@ -1180,9 +1181,9 @@ dependencies = [
 
 [[package]]
 name = "virtio-bindings"
-version = "0.2.4"
+version = "0.2.6"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "1711e61c00f8cb450bd15368152a1e37a12ef195008ddc7d0f4812f9e2b30a68"
+checksum = "804f498a26d5a63be7bbb8bdcd3869c3f286c4c4a17108905276454da0caf8cb"
 
 [[package]]
 name = "virtio-devices"
@@ -1219,9 +1220,9 @@ dependencies = [
 
 [[package]]
 name = "virtio-queue"
-version = "0.14.0"
+version = "0.16.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "872e2f3fbd70a7e6f01689720cce3d5c2c5efe52b484dd07b674246ada0e9a8d"
+checksum = "fb0479158f863e59323771a1f684d843962f76960b86fecfec2bfa9c8f0f9180"
 dependencies = [
  "log",
  "virtio-bindings",
@@ -1258,9 +1259,9 @@ source = "git+https://github.com/rust-vmm/vm-fdt?branch=main#ef5bd734f5f66fb0772
 
 [[package]]
 name = "vm-memory"
-version = "0.16.1"
+version = "0.16.2"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "f1720e7240cdc739f935456eb77f370d7e9b2a3909204da1e2b47bef1137a013"
+checksum = "1fd5e56d48353c5f54ef50bd158a0452fc82f5383da840f7b8efc31695dd3b9d"
 dependencies = [
  "arc-swap",
  "libc",
@@ -1335,14 +1336,14 @@ dependencies = [
  "vm-migration",
  "vm-virtio",
  "vmm-sys-util",
- "zerocopy 0.8.24",
+ "zerocopy 0.8.26",
 ]
 
 [[package]]
 name = "vmm-sys-util"
-version = "0.12.1"
+version = "0.14.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "1d1435039746e20da4f8d507a72ee1b916f7b4b05af7a91c093d2c6561934ede"
+checksum = "d21f366bf22bfba3e868349978766a965cbe628c323d58e026be80b8357ab789"
 dependencies = [
  "bitflags 1.3.2",
  "libc",
@@ -1367,24 +1368,24 @@ dependencies = [
 
 [[package]]
 name = "wasm-bindgen"
-version = "0.2.93"
+version = "0.2.100"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "a82edfc16a6c469f5f44dc7b571814045d60404b55a0ee849f9bcfa2e63dd9b5"
+checksum = "1edc8929d7499fc4e8f0be2262a241556cfc54a0bea223790e71446f2aab1ef5"
 dependencies = [
  "cfg-if",
  "once_cell",
+ "rustversion",
  "wasm-bindgen-macro",
 ]
 
 [[package]]
 name = "wasm-bindgen-backend"
-version = "0.2.93"
+version = "0.2.100"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "9de396da306523044d3302746f1208fa71d7532227f15e347e2d93e4145dd77b"
+checksum = "2f0a0651a5c2bc21487bde11ee802ccaf4c51935d0d3d42a6101f98161700bc6"
 dependencies = [
  "bumpalo",
  "log",
- "once_cell",
  "proc-macro2",
  "quote",
  "syn",
@@ -1393,9 +1394,9 @@ dependencies = [
 
 [[package]]
 name = "wasm-bindgen-macro"
-version = "0.2.93"
+version = "0.2.100"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "585c4c91a46b072c92e908d99cb1dcdf95c5218eeb6f3bf1efa991ee7a68cccf"
+checksum = "7fe63fc6d09ed3792bd0897b314f53de8e16568c2b3f7982f468c0bf9bd0b407"
 dependencies = [
  "quote",
  "wasm-bindgen-macro-support",
@@ -1403,9 +1404,9 @@ dependencies = [
 
 [[package]]
 name = "wasm-bindgen-macro-support"
-version = "0.2.93"
+version = "0.2.100"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "afc340c74d9005395cf9dd098506f7f44e38f2b4a21c6aaacf9a105ea5e1e836"
+checksum = "8ae87ea40c9f689fc23f209965b6fb8a99ad69aeeb0231408be24920604395de"
 dependencies = [
  "proc-macro2",
  "quote",
@@ -1416,9 +1417,12 @@ dependencies = [
 
 [[package]]
 name = "wasm-bindgen-shared"
-version = "0.2.93"
+version = "0.2.100"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "c62a0a307cb4a311d3a07867860911ca130c3494e8c2719593806c08bc5d0484"
+checksum = "1a05d73b933a847d6cccdda8f838a22ff101ad9bf93e33684f39c1f5f0eece3d"
+dependencies = [
+ "unicode-ident",
+]
 
 [[package]]
 name = "winapi"
@@ -1545,11 +1549,11 @@ dependencies = [
 
 [[package]]
 name = "zerocopy"
-version = "0.8.24"
+version = "0.8.26"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "2586fea28e186957ef732a5f8b3be2da217d65c5969d4b1e17f973ebbe876879"
+checksum = "1039dd0d3c310cf05de012d8a39ff557cb0d23087fd44cad61df08fc31907a2f"
 dependencies = [
- "zerocopy-derive 0.8.24",
+ "zerocopy-derive 0.8.26",
 ]
 
 [[package]]
@@ -1565,9 +1569,9 @@ dependencies = [
 
 [[package]]
 name = "zerocopy-derive"
-version = "0.8.24"
+version = "0.8.26"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "a996a8f63c5c4448cd959ac1bab0aaa3306ccfd060472f85943ee0750f0169be"
+checksum = "9ecf5b4cc5364572d7f4c329661bcc82724222973f2cab6f050a4e5c22f75181"
 dependencies = [
  "proc-macro2",
  "quote",
diff --git a/fuzz/Cargo.toml b/fuzz/Cargo.toml
index c4536bcfe..27bfc87ed 100644
--- a/fuzz/Cargo.toml
+++ b/fuzz/Cargo.toml
@@ -28,13 +28,13 @@ mshv-bindings = "0.5.0"
 net_util = { path = "../net_util" }
 seccompiler = "0.5.0"
 virtio-devices = { path = "../virtio-devices" }
-virtio-queue = "0.14.0"
+virtio-queue = "0.16.0"
 vm-device = { path = "../vm-device" }
 vm-memory = "0.16.0"
 vm-migration = { path = "../vm-migration" }
 vm-virtio = { path = "../vm-virtio" }
 vmm = { path = "../vmm", features = ["guest_debug"] }
-vmm-sys-util = "0.12.1"
+vmm-sys-util = "0.14.0"
 
 # Prevent this from interfering with workspaces
 [workspace]
diff --git a/hypervisor/src/kvm/mod.rs b/hypervisor/src/kvm/mod.rs
index 591a09586..8bb49e52c 100644
--- a/hypervisor/src/kvm/mod.rs
+++ b/hypervisor/src/kvm/mod.rs
@@ -44,7 +44,7 @@ pub use crate::riscv64::{
 use crate::vm::{self, InterruptSourceConfig, VmOps};
 #[cfg(target_arch = "aarch64")]
 use crate::{arm64_core_reg_id, offset_of};
-use crate::{cpu, hypervisor, vec_with_array_field, HypervisorType};
+use crate::{cpu, hypervisor, HypervisorType};
 #[cfg(target_arch = "riscv64")]
 use crate::{offset_of, riscv64_reg_id};
 // x86_64 dependencies
@@ -106,7 +106,7 @@ pub use kvm_ioctls::{Cap, Kvm, VcpuExit};
 use thiserror::Error;
 use vfio_ioctls::VfioDeviceFd;
 #[cfg(feature = "tdx")]
-use vmm_sys_util::{ioctl::ioctl_with_val, ioctl_ioc_nr, ioctl_iowr_nr};
+use vmm_sys_util::{ioctl::ioctl_with_val, ioctl_iowr_nr};
 pub use {kvm_bindings, kvm_ioctls};
 
 #[cfg(target_arch = "aarch64")]
@@ -119,8 +119,6 @@ const KVM_CAP_SGX_ATTRIBUTE: u32 = 196;
 
 #[cfg(target_arch = "x86_64")]
 use vmm_sys_util::ioctl_io_nr;
-#[cfg(all(not(feature = "tdx"), target_arch = "x86_64"))]
-use vmm_sys_util::ioctl_ioc_nr;
 
 #[cfg(target_arch = "x86_64")]
 ioctl_io_nr!(KVM_NMI, kvm_bindings::KVMIO, 0x9a);
@@ -693,10 +691,6 @@ impl vm::Vm for KvmVm {
     /// entries, as per the `KVM_SET_GSI_ROUTING` ioctl.
     ///
     fn set_gsi_routing(&self, entries: &[IrqRoutingEntry]) -> vm::Result<()> {
-        let mut irq_routing =
-            vec_with_array_field::<kvm_irq_routing, kvm_irq_routing_entry>(entries.len());
-        irq_routing[0].nr = entries.len() as u32;
-        irq_routing[0].flags = 0;
         let entries: Vec<kvm_irq_routing_entry> = entries
             .iter()
             .map(|entry| match entry {
@@ -706,17 +700,11 @@ impl vm::Vm for KvmVm {
             })
             .collect();
 
-        // SAFETY: irq_routing initialized with entries.len() and now it is being turned into
-        // entries_slice with entries.len() again. It is guaranteed to be large enough to hold
-        // everything from entries.
-        unsafe {
-            let entries_slice: &mut [kvm_irq_routing_entry] =
-                irq_routing[0].entries.as_mut_slice(entries.len());
-            entries_slice.copy_from_slice(&entries);
-        }
+        let irq_routing =
+            kvm_bindings::fam_wrappers::KvmIrqRouting::from_entries(&entries).unwrap();
 
         self.fd
-            .set_gsi_routing(&irq_routing[0])
+            .set_gsi_routing(&irq_routing)
             .map_err(|e| vm::HypervisorVmError::SetGsiRouting(e.into()))
     }
 
@@ -2956,11 +2944,15 @@ impl KvmVcpu {
     ///
     fn set_xsave(&self, xsave: &XsaveState) -> cpu::Result<()> {
         let xsave: kvm_bindings::kvm_xsave = (*xsave).clone().into();
-        self.fd
-            .lock()
-            .unwrap()
-            .set_xsave(&xsave)
-            .map_err(|e| cpu::HypervisorCpuError::SetXsaveState(e.into()))
+        // SAFETY: Here we trust the kernel not to read past the end of the kvm_xsave struct
+        // when calling the kvm-ioctl library function.
+        unsafe {
+            self.fd
+                .lock()
+                .unwrap()
+                .set_xsave(&xsave)
+                .map_err(|e| cpu::HypervisorCpuError::SetXsaveState(e.into()))
+        }
     }
 
     #[cfg(target_arch = "x86_64")]
diff --git a/virtio-devices/Cargo.toml b/virtio-devices/Cargo.toml
index fd86b5e3c..5056fd1ac 100644
--- a/virtio-devices/Cargo.toml
+++ b/virtio-devices/Cargo.toml
@@ -36,7 +36,7 @@ vhost = { workspace = true, features = [
   "vhost-user-frontend",
   "vhost-vdpa",
 ] }
-virtio-bindings = { workspace = true, features = ["virtio-v5_0_0"] }
+virtio-bindings = { workspace = true }
 virtio-queue = { workspace = true }
 vm-allocator = { path = "../vm-allocator" }
 vm-device = { path = "../vm-device" }
diff --git a/virtio-devices/src/vdpa.rs b/virtio-devices/src/vdpa.rs
index 7a8952f21..decd6ede6 100644
--- a/virtio-devices/src/vdpa.rs
+++ b/virtio-devices/src/vdpa.rs
@@ -16,7 +16,8 @@ use vhost::vhost_kern::vdpa::VhostKernVdpa;
 use vhost::vhost_kern::vhost_binding::VHOST_BACKEND_F_SUSPEND;
 use vhost::vhost_kern::VhostKernFeatures;
 use vhost::{VhostBackend, VringConfigData};
-use virtio_queue::{Descriptor, Queue, QueueT};
+use virtio_queue::desc::RawDescriptor;
+use virtio_queue::{Queue, QueueT};
 use vm_device::dma_mapping::ExternalDmaMapping;
 use vm_memory::{GuestAddress, GuestAddressSpace, GuestMemory, GuestMemoryAtomic};
 use vm_migration::{Migratable, MigratableError, Pausable, Snapshot, Snapshottable, Transportable};
@@ -245,7 +246,7 @@ impl Vdpa {
                 flags: 0u32,
                 desc_table_addr: queue.desc_table().translate_gpa(
                     self.common.access_platform.as_ref(),
-                    queue_size as usize * std::mem::size_of::<Descriptor>(),
+                    queue_size as usize * std::mem::size_of::<RawDescriptor>(),
                 ),
                 used_ring_addr: queue.used_ring().translate_gpa(
                     self.common.access_platform.as_ref(),
diff --git a/virtio-devices/src/vhost_user/vu_common_ctrl.rs b/virtio-devices/src/vhost_user/vu_common_ctrl.rs
index 60ee6b32d..e1204fbd7 100644
--- a/virtio-devices/src/vhost_user/vu_common_ctrl.rs
+++ b/virtio-devices/src/vhost_user/vu_common_ctrl.rs
@@ -18,7 +18,8 @@ use vhost::vhost_user::{
     Frontend, FrontendReqHandler, VhostUserFrontend, VhostUserFrontendReqHandler,
 };
 use vhost::{VhostBackend, VhostUserDirtyLogRegion, VhostUserMemoryRegionInfo, VringConfigData};
-use virtio_queue::{Descriptor, Queue, QueueT};
+use virtio_queue::desc::RawDescriptor;
+use virtio_queue::{Queue, QueueT};
 use vm_memory::{
     Address, Error as MmapError, FileOffset, GuestAddress, GuestMemory, GuestMemoryRegion,
 };
@@ -212,7 +213,7 @@ impl VhostUserHandle {
                 desc_table_addr: get_host_address_range(
                     mem,
                     GuestAddress(queue.desc_table()),
-                    actual_size * std::mem::size_of::<Descriptor>(),
+                    actual_size * std::mem::size_of::<RawDescriptor>(),
                 )
                 .ok_or(Error::DescriptorTableAddress)? as u64,
                 // The used ring is {flags: u16; idx: u16; virtq_used_elem [{id: u16, len: u16}; actual_size]},
diff --git a/vm-virtio/src/queue.rs b/vm-virtio/src/queue.rs
index 4e55cc4b5..c33f6e599 100644
--- a/vm-virtio/src/queue.rs
+++ b/vm-virtio/src/queue.rs
@@ -12,7 +12,8 @@ pub mod testing {
     use std::marker::PhantomData;
     use std::mem;
 
-    use virtio_queue::{Queue, QueueT, VirtqUsedElem};
+    use virtio_queue::desc::split::VirtqUsedElem;
+    use virtio_queue::{Queue, QueueT};
     use vm_memory::bitmap::AtomicBitmap;
     use vm_memory::{Address, Bytes, GuestAddress, GuestUsize};